Methylguanine Methyltransferase MGMT Test
Introduction to the MGMT Test
The Methylguanine Methyltransferase (MGMT) Test is a critical diagnostic tool used in oncology to evaluate the methylation status of the MGMT gene. This gene plays a vital role in DNA repair mechanisms, particularly in the context of cancer treatment. Understanding the methylation status of MGMT can significantly influence treatment decisions, especially in patients with glioblastoma and other cancers where the effectiveness of certain chemotherapeutic agents may be impacted.
What the Test Measures
The MGMT Test measures the methylation status of the MGMT gene. Methylation can silence the gene, which may lead to reduced DNA repair capability and increased sensitivity to alkylating agents used in chemotherapy. By determining whether the MGMT gene is methylated or unmethylated, healthcare providers can better predict a patient’s response to specific cancer treatments.
Who Should Consider This Test?
This test is recommended for:
- Patients diagnosed with glioblastoma or other types of cancer where MGMT status may influence treatment options.
- Individuals with a family history of cancer or those showing symptoms that may indicate a genetic predisposition to malignancies.
- Patients who are considering chemotherapy and want to understand their potential response to treatment.
Benefits of Taking the Test
Taking the MGMT Test offers several benefits:
- Informs treatment decisions, allowing for personalized cancer therapy.
- Helps oncologists identify patients who may benefit from specific chemotherapeutic agents.
- Provides insights into prognosis and potential treatment outcomes.
Understanding Your Results
Results from the MGMT Test will indicate whether the MGMT gene is methylated or unmethylated.
- Methylated: Indicates a potential increased sensitivity to alkylating agents, suggesting these treatments may be more effective.
- Unmethylated: Suggests that the MGMT gene is active, which may lead to resistance against certain chemotherapy drugs.
It is essential to discuss your results with your oncologist to understand the implications for your treatment plan.
Test Details and Pricing
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Methylguanine Methyltransferase MGMT Test | 1,200,000 NGN | 1,600,000 NGN |
How to Book the Test
Booking the Methylguanine Methyltransferase MGMT Test is easy! Simply contact us at DNA Labs Nigeria. For inquiries and appointments, please call or WhatsApp us at +2348077798758. Ensure you have a duly filled Genomics Clinical Information Requisition Form (Form 20) ready before your appointment.
Test Specifications
- Turnaround Time: Sample must be submitted by 11 am on Monday; reports are available in 13 working days.
- Sample Type: Blood, Buccal Swab, Plasma
- Department: Molecular Diagnostics
- Method: PCR
- Specialty: Oncologist
- Disease Type: Cancer
